sghsgh

This wall quilt uses EPP hexagons to represent a DNA sequence that is appliqued onto a background and then quilted. The layout was prototyped using EQ7. The A's, C's, T's and G's are represented by 'logo pairs' carved onto stamp material and then stamped on the central hexagons with Tsukineko Ink. The sequence is a small part of the estrogen receptor gene (ESR1), an important gene in normal life but also a driver in breast cancer. It includes a mutation, shown in black ink (K303R), that causes an amino acid change at the 303 position and may lead to therapy resistance. The quilt was made as a gift for my friend, Dr. Suzanne Fuqua, who pioneered the study of ESR1 mutations and has scientific publications on this variant (listed as the background of the label) spanning 25 years. The background, backing and binding fabrics are all used with the 'wrong-side' out to tone down the designs and mute the colors. https://susieturn.blogspot.com/2016/10/esr1-k303r.html