Oh, wow......so much to say here!
The easiest way is to choose a premade block in EQ7, from the block library, and then choose your quilt setting, and set the block. This gives you a fairly traditional quilt, although you can mix and match several blocks, etc.
A step up from that is to do "custom layout" where you can set your blocks to any position, size, etc. You set the size of the quilt, but then you click and drag the block to where you want it, and then can resize it. You do this for all the blocks you want in the quilt.
A step up from that is to open a block in the Block worktable and erase lines, add lines, etc. to create your own block. Or use their Serendipity tool to merge blocks. Then create the quilt layout as above.
Then stepping up from that is to draw your own. I've only done one that way, and I still find it very difficult to draw freehand shapes (if you are doing geometric shapes it is fine). Correction, I did two that way. still -- it's difficult at times, though there are loads of videos in the "help" files of EQ7 to teach you how to do it. If you have time and inclination to go through step by step and work through the classes/videos (in the software, and on their blog), that will help tons.
I'm running out the door for the day, but I will try and come back to follow-up if you have any questions, although I am not an expert by any means. I do use it, to design layouts, but I don't draw my own blocks much. Still, if you have questions, I can try to answer them, or maybe someone else will chime in