I used a small flower shaped trim, similar to ric rac, on a baby quilt I made. I was doing criss-crosses (x) over the top of diamonds, to be the skinny part of an argyle design, so I put the ric rac on each section of the quilt before I joined the sections together (there were 3 vertical sections) so that the ric rac would be caught in the seams for extra safety since it was for a baby.
I quilted it on my regular machine, with a walking foot; it wasn't hard to quilt over at all. The quilt has only been washed the once so far (still haven't delivered it to the baby), but there was not any shrinking or puckering or anything in the trim. Although, I do not pre-wash my fabrics, either, so.... Anyway, it was fine.
This is a small normal sized trim, though, not the giant kind that Camille sometimes shows/uses.