Eileen, it's not a problem if you use the fusible stuff only around the edges of each shape.
Personally I wouldn't comtemplate hand appliqué (and I love all sorts of embroidery) if there is a lot of it on a large bed quilt. It would be a question of time for me. Whichever way you look at it, machine appliqué is quicker.
Talking about 'stiff appliqué shapes': I have always wanted to make a set of small, identical pieces, using all the different fusibles on the market and compare afterwards how they feel, handle, wash, and wear........ Ah well, I'll look into that when I retire in 2016.
Lorchen