I really think that organizing your time is even more important than organizing your space. Quilting is Sue's job. She spends at least as much time each day in her studio as you working ladies spend commuting and putting in a full day (and more?) at work. And she always has a hand project to take when she needs to be away from her wonderful studio.
As for me, I am fortunate that I have been able to expand my quilting space since our children left for college. As for time, since my husband's cancer diagnosis in 2007, we have been house-bound for long stretches of time, and I've been able to get a lot of concentrated time in the sewing room since then. Because we are both retired, that also frees up a lot of time to devote to things that give us pleasure. Mine is quilting, his is golf when he feels up to it now.
Before that, I made quilting a priority when I wanted to get something done. I would schedule time to quilt on my calendar, just like I scheduled important appointments, like the doctor's visits for DH and his mother. (I'm also her caregiver.) I would set aside whole days or half days and would go into the sewing room and WORK.
People with more obligations (job, children, church, volunteer work) may not be able to set aside whole or half days, but you can set aside a solid hour for concentrated work. You need to MAKE time to quilt. If you just wait until you FIND time, it probably won't happen. Something else will get done, but quilting is easily set aside if it's not a priority.
When I head to the sewing room, I am on a mission. I know what I'm going to work on, and know that I work better in a neat environment, so the first thing I do is put away anything that may have been left out of place the last time I worked so I can concentrate on one thing at a time. I guess I'm not good at multi-tasking.
I don't really have a lot of UFOs because I either finish what I'm working on or decide that it has taught me some kind of lesson and I can abandon it. I do have several projects going at a time, but they don't drag on and on.
I hope that answers some of your questions about how I work. I'm looking forward to seeing what others do!