Fleece probably slides better than flannel, huh? The flannel back on one of my quilts doesn't slide at all and that really surprised me. I think it was both a weight and a surface thing. On a small quilt, the slide factor might not matter that much though. Have fun!

Sure, I do it all the time, especially for kids quilts.

I usually use a piece of flannel for batting so it won't be so thick. But I've done it without batting also. Your stitches can get lost in the fleece so you might want to lengthen your stitch. Machine quilting right? I wouldn't try hand quilting with this.

You're binding can be a problem also. You can make a wider binding, to help with the thickness, you can fold the fleece backing over to the front and not use a separate batting, or once I put that wide satiny baby binding on with a zigzig stitch, fast!! and looked great!! )

I am making a baby quilt for my yet-to-be-born granddaughter (first one, due in Sept.). I have a lovely collection of pink and green cottons that match the paint chips for "Charlotte's" room. However, today I spotted a wonderful piece of fleece - PINK CHICAGO CUBS LOGOS. My son and his wife are avid Cubs fans and I think it would be great to combine sweet little-girl stuff with sports passion on the back.
What are the potential problems that I might have combining the cotton with the fleece? I will not use a batting. Any and all suggestions are welcome, including what thread I should use.
Thanks.